SIEH is structured into three main areas:

• Business Innovation Centre, dedicated to supporting the creation and growth of new entrepreneurial initiatives and guiding businesses through innovation processes.
• Saperi&Co Centre, a collaborative space for interdisciplinary engagement between research, industry, and institutions aimed at the co-creation of innovative solutions and the development of advanced skills.
• Yunus Social Business Centre, focused on promoting social business and entrepreneurial models oriented towards social and environmental impact.

SIEHub serves as a reference point for enhancing research results, attracting talent, and spreading a sustainable and inclusive entrepreneurial culture. It represents a strategic commitment of Sapienza University of Rome – the largest university in Europe, with a centuries-old tradition of excellence in education and research – to strengthen the bond between knowledge and enterprise and to contribute actively to the country’s innovation and growth.