Department of Defense (DoD) Funding Opportunities

DoD SBIR 2025.4

• Release 5: Nine topics – Army, Defense Advanced Research Projects Agency (DARPA)

• Release 6: Three topics – Army, Defense Health Agency (DHA)

• Release 7: Eight topics – Army, Defense Logistics Agency (DLA)

• Release 8: 68 topics – Army, U.S. Air Force, DARPA, Missile Defense Agency (MDA)

• Topics are pre-released on the first Wednesday of every month.

DoD SBIR CSO X25.5

• Three topics – U.S. Air Force (USAF)
• Topics are pre-released on the first Wednesday of every month.

DoD STTR 2025.D 

• Release 7: Four topics – Army, Chemical and Biological Defense Program (CBD), Special Operations Command (SOCOM)
• Release 8: 21 topics – Army, U.S. Air Force (USAF), Office of the Secretary of Defense (OSD)   
• Topics are pre-released on the first Wednesday of every month.

Air Force SBIR CSO X25.6 

• Five topics – U.S. Air Force Pre-Release: May 7, 2025
• Open: May 28, 2025
• Close: June 25, 2025 

DoD SBIR 2025.2 – Open Topics

• 25 topics: Defense Health Agency (DHA), Defense Threat Reduction Agency (DTRA), Navy, Office of the Secretary of Defense (OSD)  
• Pre-Release: April 2, 2025
• Open: April 23, 2025
• Close: May 21, 2025

DoD STTR 2025.B 

• 15 topics – Missile Defense Agency (MDA)
• Pre-Release: April 2, 2025
• Open: April 23, 2025
• Close: May 21, 2025 

 

Department of the Navy (DON) 25.2/25.B Deadline

The DON 25.2 SBIR and 25.B STTR Broad Agency Announcements (BAAs) will close for proposal submissions on May 21, 2025, at 12:00 PM ET. This BAA contains 56 topics (48 SBIR Phase I, 3 SBIR Direct to Phase II, and 5 STTR Phase I) from six DON Systems Commands: Marine Corps Systems Command (MCSC), Naval Air Systems Command (NAVAIR), Naval Sea Systems Command (NAVSEA), Naval Information Warfare Systems Command (NAVWAR), Office of Naval Research (ONR), and Strategic Systems Programs (SSP). For the complete list of technology areas and instructions, visit the website above.

• Pre-Release: April 2, 2025
• Open: April 23, 2025
• Close: May 21, 2025

 

National Aeronautics and Space Administration (NASA) Phase II-Extended (II-E)

Phase II-E awards often act as the “bridge” between Phase II and other Post-Phase II Opportunities by promoting further research and development (R&D) efforts and supporting the commercialization of innovations that have been developed under the Phase II contract. Phase II-E reduces risk by allowing an investor to contribute funds that the NASA SBIR/STTR program will match, up to $375,000, for an additional funding total of $750,000 on top of a company’s Phase II award.

• The next cutoff date for Phase II-E applications is May 16, 2025. 

National Science Foundation (NSF) SBIR/STTR Phase I and II Programs

The NSF SBIR/STTR programs provide non-dilutive funds for use-inspired research and development (R&D) of unproven, leading-edge technology innovations that address societal challenges.

• NSF 24-579
• NSF 24-580  
• Posted Date: May 31, 2024
• Close Dates: July 2, 2025, and November 5, 2025 

National Institutes of Health (NIH) SBIR/STTR Omnibus Notice to Extend the Expiration Date of PA-24-246 PHS 2024-2 Omnibus Solicitation of the NIH and CDC for SBIR Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)

• PA-24-246 will now expire on September 6, 2025. 

National Institutes of Standards and Technology (NIST) FY 2025 SBIR Phase II

NIST has released its SBIR FY2025 Phase II Notice of Funding Opportunity (NOFO) No. 2025-NIST-SBIR-02.

• Only previous FY24 Phase I award recipients at NIST are eligible to apply.  
• Posted: April 16, 2025
• Close: June 14, 2025 

Other Funding Opportunities

National Aeronautics and Space Administration (NASA): Sustainable Business Challenge

NASA invites entrepreneurs, startups, researchers, and innovators to apply for a brand-new opportunity – sponsored by the NASA SBIR/STTR program – to use NASA’s publicly available climate and Earth systems science data sources to create sustainable business models to address climate challenges.

• Applications are due by June 13, 2025. 

• Up to 10 winners will each receive $10,000, with a total prize pool of $100,000