This program seeks to prepare, nurture, and grow the national scientific research workforce for creating, utilizing, and supporting advanced cyberinfrastructure (CI) to enable and potentially transform fundamental science and engineering (S&E) research and education and contribute to the Nation’s overall economic competitiveness and security. The goals of this solicitation are to ensure broad adoption of CI tools, methods, and resources by the research community in order to catalyze major research advances and to enhance researchers’ abilities to lead the development of new CI; integrate core literacy and discipline-appropriate advanced skills in advanced CI as well as computational and data-driven methods for advancing fundamental research, into the Nation’s undergraduate and graduate educational curriculum/instructional materials; and (iii) build communities of research CI professional staff to deploy, manage, and collaboratively support the effective use of research CI, as well as establish career paths for those staff within and across institutions and science and engineering (S&E) disciplines.